Question

the following pedigree shows the inheritance of an autosomal recessive condition. what are the chances that the female in generation ii is a carrier for this condition? generation i 1 2 3 4 ii 1 2 iii 1 2 3 4 5 6 female male unaffected individual affected individual click or tap a choice to answer the question. 0% 33% 50% 75% 100%

Explanation:

Step1: Determine the genotype of generation I - 2

Since the condition is autosomal recessive, generation I - 2 (affected) has genotype \(aa\). Generation I - 1 is unaffected, so its genotype is \(Aa\) (because it has an affected offspring).

Step2: Analyze the cross between generation I - 1 (\(Aa\)) and generation I - 2 (\(aa\))

The possible genotypes of their offspring (generation II) from the cross \(Aa\times aa\) are \(Aa\) and \(aa\) in a \(1:1\) ratio. But generation II - 1 is unaffected (not \(aa\)), so the possible genotypes are only \(Aa\).

Answer:

100%