Question

essential nutrients that are required in relatively large quantities and play principal roles in cell structure and metabolism are

o trace elements
o metabolites
o macronutrients
o micronutrients

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Explanation:

Macronutrients are essential nutrients required in relatively large quantities. They play principal roles in cell structure (e.g., proteins as structural components) and metabolism (e.g., carbohydrates as energy sources, lipids in energy storage and membrane structure). Micronutrients (like vitamins and some minerals) are needed in smaller amounts. Trace elements are a type of micronutrient. Metabolites are the intermediates and products of metabolism, not the initial nutrients required in large amounts for cell structure and major metabolic pathways.

Answer:

macronutrients