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Question
a company has developed a detergent that disrupts biological membranes by mimicking the structure of their phospholipids. it is most likely that the active ingredient
o has a long polar \tail\ that inserts into the hydrophobic core of the phospholipid bilayer, preventing stacking of the fatty acids.
o has a highly charged polar \head\ that binds to membrane phospholipids, causing them to flip their orientation and scatter in the aqueous environment.
o is composed of a chain of carbohydrates that inserts into the hydrophilic core of the membrane, preventing stacking between other phospholipids.
o is a large non - polar lipid that binds the polar \heads\ of the phospholipid bilayer, neutralizing their charge and attraction to one another.
o has both a polar end and a non - polar end that inserts into the membrane, disturbing the interaction between existing phospholipids.
Phospholipids have a polar head and non - polar tail. A detergent mimicking phospholipids would also have both polar and non - polar parts. The non - polar part can interact with the non - polar tails of membrane phospholipids, and the polar part can interact with the polar heads or the aqueous environment. This dual nature (amphipathic) allows it to insert into the membrane and disrupt the interactions between existing phospholipids.
- Option 1: The tail of phospholipids is non - polar, not polar. So this option is incorrect.
- Option 2: While the head is polar, just binding and causing flipping is not the most accurate mimicry of phospholipid structure (which has both polar and non - polar parts).
- Option 3: Phospholipids are not composed mainly of carbohydrates. The core of the membrane (where tails are) is hydrophobic, not hydrophilic.
- Option 4: Phospholipid heads are polar, and a non - polar lipid binding to them is not a mimicry of phospholipid structure.
- Option 5: Having both polar and non - polar ends (amphipathic) is similar to phospholipids and can disrupt membrane structure.
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The fifth option: has both a polar end and a non - polar end that inserts into the membrane, disturbing the interaction between existing phospholipids.