Question

after chromosomes are formed, during which phase of mitosis do the chromosomes attach to the spindle fibers by their centromeres?

anaphase
prophase
metaphase
telophase

Explanation:

To solve this, we analyze each mitosis phase:

• Anaphase: Sister chromatids separate and move to opposite poles. Not when attachment occurs.
• Prophase: Chromosomes condense, spindle forms, but attachment isn't here.
• Metaphase: Chromosomes align at the equator, attached to spindle fibers via centromeres (kinetochores). This matches the question.
• Telophase: Nuclear envelopes reform, chromosomes decondense. Not related to attachment.

Answer:

C. metaphase