Question

15 multiple choice 1.5 points if an affected individual with a rare recessive mutation is married to a normal individual, whats the chance for their children to be affected? 0 1/4 1/2 1/1 (100%)

Explanation:

Let the recessive mutation be represented by 'a'. The affected individual has genotype 'aa'. The normal individual can be either 'AA' or 'Aa'. Since the mutation is rare, the normal individual is most likely 'AA'. When 'aa' (affected) and 'AA' (normal) have children, all children will have the genotype 'Aa' and will not be affected. So the probability of affected children is 0.

Answer:

A. 0