Question

1. the first large - scale effort by the united states government to regulate business involved --

○ adoption of the eighteenth amendment
○ passage of the sherman anti - trust act
○ creation of the food and drug administration
○ establishment of the interstate commerce commission

Explanation:

To determine the first large - scale U.S. government business regulation effort, we analyze each option:

• The Eighteenth Amendment was about Prohibition (banning alcohol), not business regulation.
• The Sherman Anti - trust Act (1890) was for anti - monopoly, but the Interstate Commerce Commission (ICC, 1887) was the first federal regulatory agency, established to regulate railroad rates and practices, marking the first large - scale business regulation. The Food and Drug Administration was created later. So the correct option is the establishment of the Interstate Commerce Commission.

Answer:

D. establishment of the Interstate Commerce Commission