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Question
wolf-hirschhorn syndrome affects the faces of the individuals who are suffering from it. the short arm of their chromosome 4 is missing a piece. what kind of chromosomal mutation is this?
deletion
translocation
inversion
duplication
Chromosomal deletion means a part of a chromosome is lost. In Wolf - Hirschhorn syndrome, a piece of the short arm of chromosome 4 is missing, which fits the definition of deletion. Translocation is when a part of a chromosome attaches to another non - homologous chromosome. Inversion is when a segment of a chromosome is reversed. Duplication is when a segment of a chromosome is copied. Since the problem states a piece is missing (not moved, reversed, or copied), deletion is the correct answer.
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deletion