Question

which issue is related to long - term marijuana use? brain damage difficulty thinking mood swings altered senses

Explanation:

Long - term marijuana use can have various cognitive and psychological impacts. It can affect brain function leading to difficulty thinking. While brain damage is a more extreme and less common direct result, mood swings and altered senses are more short - term or acute effects compared to the cognitive impairment of difficulty thinking related to long - term use.

Answer:

difficulty thinking