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Question
which of the following is the disease of the heart muscle that is not only congenital, but is also a genetic problem due to glycogen accumulation? gaucher disease mcardle disease pompe disease tay - sachs disease
Pompe disease is a genetic disorder caused by the deficiency of the enzyme acid alpha - glucosidase, leading to glycogen accumulation in various tissues, especially the heart muscle. It can be congenital. Gaucher disease is related to lipid metabolism (glucocerebroside accumulation), McArdle disease (glycogen storage disease type V) mainly affects skeletal muscle (not heart muscle in the context of the question's description), and Tay - Sachs disease is related to lipid (GM2 ganglioside) accumulation in nerve cells.
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Pompe disease