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Question
when during the cell cycle would you expect to find cohesin protein associated with chromosomes? select all that apply. marks will be removed for incorrect selection(s). select one or more: a. g1 phase b. metaphase c. prophase d. telophase
Cohesin proteins hold sister chromatids together after DNA replication. They associate with chromosomes during G1, remain through S phase (when replication occurs), and stay until anaphase. G1 phase: cohesin loads onto chromosomes before replication. Prophase: sister chromatids are intact, so cohesin is present. Metaphase: sister chromatids are aligned, cohesin still holds them. Telophase: sister chromatids have separated, so cohesin is no longer associated.
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a. G1 phase, b. Metaphase, c. Prophase