Question

what is required for formation of the transcription initiation complex in eukaryotes? multiple choice binding of a transcription factor to the tata box, followed by recruitment of additional transcription factors and recruitment of rna polymerase ii binding of a transcription factor to the transcription bubble, followed by recruitment of additional transcription factors and recruitment of rna polymerase ii binding of the sigma subunit to the start site followed by recruitment of rna polymerase ii binding of rna polymerase ii to the tata box, followed by recruitment of transcription factors binding of the sigma subunit to promoter elements at - 35 and - 10, followed by recruitment of the core polymerase

Explanation:

In eukaryotes, the formation of the transcription - initiation complex begins with a transcription factor binding to the TATA box in the promoter region. This is followed by the recruitment of additional transcription factors and then the recruitment of RNA polymerase II. The TATA box is a key regulatory DNA sequence. The sigma subunit is involved in prokaryotic transcription initiation, not eukaryotic. The transcription bubble forms during the elongation phase of transcription, not during initiation complex formation. RNA polymerase II binds after transcription factors have assembled at the promoter.

Answer:

Binding of a transcription factor to the TATA box, followed by recruitment of additional transcription factors and recruitment of RNA polymerase II