Question

target writing level: advanced
choose a genetic disorder to research and then complete the following writing prompt:
write an essay describing your chosen genetic disorder. include information about the genetic mutation that causes the disorder, the effects and symptoms of the mutation, how it is acquired, and how common it is.
hint:
genetic disorders are caused by mutations in the dna. these mutations can be passed on from the parents, occur spontaneously, or develop over time.
questions to consider:

• is there anyone famous or important who has ever had this disorder?
• does the disorder have any advantages?

write at least 150 words.

Explanation:

To complete this essay, first choose a genetic disorder like sickle - cell anemia. Research its genetic mutation (a single - nucleotide substitution in the HBB gene). Explain symptoms (painful crises, anemia), how it's acquired (autosomal recessive inheritance), and its prevalence (common in populations with malaria exposure). Mention famous figures if applicable (though not many for sickle - cell specifically). Discuss if there are advantages (protection against malaria in carriers). Structure the essay with an introduction, body paragraphs for each required aspect, and a conclusion.

Answer:

Here is an example essay on sickle - cell anemia:

Sickle - Cell Anemia

Sickle - cell anemia is a genetic disorder caused by a mutation in the HBB gene. This mutation leads to the production of abnormal hemoglobin, which causes red blood cells to take on a sickle shape.

The symptoms of sickle - cell anemia are diverse. Patients often experience painful crises due to the blockage of blood vessels by the sickle - shaped cells. Anemia is also a common symptom as the abnormal cells have a shorter lifespan.

It is acquired in an autosomal recessive manner. A person must inherit two copies of the mutated gene (one from each parent) to develop the full - blown disease. Carriers (with one normal and one mutated gene) have some protection against malaria.

Sickle - cell anemia is relatively common in regions where malaria is prevalent, such as sub - Saharan Africa. While there are no clear "advantages" for those with the full - blown disease, carriers have an evolutionary advantage in malaria - infested areas. In conclusion, sickle - cell anemia is a complex genetic disorder with significant impacts on health and an interesting evolutionary aspect related to its prevalence.