Question

select the correct answer.

which mutation does the given change in nucleotide sequence represent?

attgcatc \\(\
ightarrow\\) atacgttc

translocation
substitution
inversion
duplication

Explanation:

Compare the original and mutated sequences

Original: A T T G C A T C
Mutated: A T A C G T T C

Identify the segment that has changed

The first two bases (A T) and the last two bases (T C) remain identical:
Original: A T [T G C A] T C
Mutated: A T [A C G T] T C

Analyze the nature of the change

The middle segment T G C A is reversed (inverted) to become A C G T:

• Original middle: 5'-T-G-C-A-3'
• Reversed middle: 5'-A-C-G-T-3'

This represents an inversion mutation.

Answer:

• translocation
• substitution
• inversion (Correct answer)
• duplication