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question 1 - 6 oligomycin is an antibiotic that blocks atp synthase, a …

Question

question 1 - 6
oligomycin is an antibiotic that blocks atp synthase, a protein that aids in the synthesis of atp.
which statement explains how oligomycin might affect the cells of a person taking this antibiotic?
it would reduce electron flow through the electron transport chain, decreasing the amount of atp, and thus energy, available to the cell.
it would allow for the attachment of a phosphate group to atp, transferring energy to the cell.
it would prohibit the cell from producing an abundance of atp, requiring the cell to carry out higher levels of fermentation.
it would increase the rate of cellular respiration, requiring the cell to produce more atp to regulate the carbon dioxide waste.

Explanation:

Brief Explanations

ATP synthase is involved in the final step of cellular respiration (oxidative phosphorylation) where a large amount of ATP is produced. The electron transport chain generates a proton gradient which ATP synthase uses to make ATP. If oligomycin blocks ATP synthase, the electron flow through the electron transport chain (which is coupled to ATP synthesis) would be affected. When ATP synthase is blocked, the electron transport chain's normal operation is disrupted. The electron flow through the electron transport chain is necessary for the generation of the proton - motive force (PMF) which drives ATP synthesis. If ATP synthesis is blocked (by oligomycin), the electron flow through the electron transport chain is reduced (because the processes are coupled). This reduction in electron flow means less ATP is produced (as ATP synthesis is dependent on electron flow through the chain to build the PMF), and thus less energy is available to the cell.

Answer:

It would reduce electron flow through the electron transport chain, decreasing the amount of ATP, and thus energy, available to the cell.