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question 3 (mandatory) (1 point)
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with pernicious anemia what shape are the cells?
a) microcytic
b) normocytic
c) macrocytic
d) hypochromic
Pernicious anemia is a type of megaloblastic anemia. In megaloblastic anemias (including pernicious anemia), there is impaired DNA synthesis in erythroid precursors. This leads to abnormal nuclear - cytoplasmic development as the nucleus matures more slowly than the cytoplasm. As a result, large (macrocytic) red blood cells are produced. Microcytic cells are seen in iron - deficiency anemia, normocytic cells in some acute blood loss or chronic diseases (in the early stages), and hypochromic cells are related to reduced hemoglobin content (also seen in iron - deficiency anemia).
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C. Macrocytic