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Question
question: how does dna make a copy of itself?
- observe: an enzyme is a protein that facilitates certain cell processes. drag the blue dna helicase enzyme onto the dna strand. what does this enzyme do to the dna molecule?
- observe: drag the yellow dna polymerase molecule onto the dna strand. dna polymerase adds complementary nucleotides to create new double - stranded dna molecules. notice two groups of nucleotides on the right.
a. drag one of the nucleotides to a corresponding nitrogenous base on one of the two strands. what is the role of dna polymerase in this process?
b. continue adding nucleotides to both strands. what happens to the dna polymerase molecule each time you add a nucleotide?
c. complete the two dna molecules. how do these molecules compare to each other?
- compare:
how are the \daughter dna molecules.\ molecules compared to the original?
congratulations! you have completed the process of replication, where one \parent\ dna strand divides to form two identical \daughter\ dna strands.
- think and discuss: why is dna replication such an important process?
- extend your thinking: sometimes errors called mutations occur during dna replication. what are some of the possible consequences of mutations?
- DNA helicase unwinds and separates the DNA double - helix.
2.
- A. DNA polymerase catalyzes the addition of nucleotides to the growing DNA strand.
- B. The DNA polymerase molecule moves along the DNA strand as each nucleotide is added.
- C. The two DNA molecules are identical to each other.
- The "Daughter DNA molecules" are identical to the original DNA molecule.
- DNA replication is important because it ensures that each new cell has a complete set of genetic information. This is necessary for cell division (both mitosis and meiosis), growth, repair, and reproduction. Without accurate DNA replication, cells would not be able to function properly as they would lack the correct genetic instructions.
- Some possible consequences of mutations:
- Beneficial mutations: Can lead to new traits that may be advantageous in a particular environment. For example, a mutation in a plant might make it more resistant to a certain pest or drought.
- Neutral mutations: May have no significant effect on the organism's phenotype. Since many parts of the DNA are non - coding or the mutation occurs in a region where the change in the amino acid sequence (if it is a coding region) does not affect the protein's function.
- Harmful mutations: Can cause genetic disorders. For example, sickle - cell anemia is caused by a mutation in the gene that codes for hemoglobin. This mutation changes the shape of red blood cells, leading to a variety of health problems such as pain, organ damage, and an increased risk of infection.
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- DNA helicase unwinds and separates the DNA double - helix.
2.
- A. DNA polymerase catalyzes the addition of nucleotides to the growing DNA strand.
- B. The DNA polymerase molecule moves along the DNA strand as each nucleotide is added.
- C. The two DNA molecules are identical to each other.
- The "Daughter DNA molecules" are identical to the original DNA molecule.
- DNA replication is important because it ensures that each new cell has a complete set of genetic information. This is necessary for cell division (both mitosis and meiosis), growth, repair, and reproduction. Without accurate DNA replication, cells would not be able to function properly as they would lack the correct genetic instructions.
- Some possible consequences of mutations:
- Beneficial mutations can lead to new traits that may be advantageous in a particular environment.
- Neutral mutations may have no significant effect on the organism's phenotype.
- Harmful mutations can cause genetic disorders.