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Question
question 2
george is a carrier for sickle cell anemia, an autosomal recessive disorder, while georgette is affected. what are the odds that their future child will be a carrier?
a 1/2
b 1/8
c 1/3
d 3/8
e 3/4
f 1/6
g 0
h 2/3
i 1/4
Step1: Determine genotypes
Let \( S \) represent the normal allele and \( s \) represent the sickle - cell allele. Since sickle - cell anemia is autosomal recessive, George (a carrier) has the genotype \( Ss \), and Georgette (affected) has the genotype \( ss \).
Step2: Use Punnett square
| \( S \) | \( s \) | |
|---|---|---|
| \( s \) | \( Ss \) | \( ss \) |
The possible genotypes of their children are \( Ss \) (carrier) and \( ss \) (affected). There are 2 out of 4 possible genotypes that are \( Ss \).
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A. \( 1/2 \)