Question

a protein is made up of two folded chains of amino acids. one is 328 amino acids in length and the other is 252 amino acids in length. which of these situations could disrupt the function of this protein?
a change of two amino acids in the shorter chain occurs.
one of the chains is not made at all.
a single amino acid change occurs in the longer chain.
any change occurring in one or both of the chains.
a loss of seven amino acids from the shorter chain occurs.

Explanation:

Protein function depends on the correct structure of all its subunits (chains). If one chain is missing, the protein cannot form its functional quaternary structure, so its function is disrupted. Amino acid changes may or may not affect function (e.g., silent changes or changes in non-critical regions), and not all changes guarantee disruption. Missing an entire chain is a severe defect that eliminates functional structure.

Answer:

B. One of the chains is not made at all.