Question

a nurse is caring for a client who has a gynecologic infection and a history of alcohol use disorder. the nurse should identify that which of the following medications can cause a reaction similar to disulfiram if the client drinks alcohol while taking it? (select all that apply.)
□ metronidazole
□ amoxicillin
□ acyclovir
□ cefotetan
□ miconazole

Explanation:

To determine which medications cause a disulfiram - like reaction with alcohol, we analyze each option:

• Metronidazole: It is known to interact with alcohol, producing a disulfiram - like reaction. This reaction includes symptoms such as nausea, vomiting, flushing, and rapid heart rate.
• Amoxicillin: This is a penicillin - type antibiotic and does not have a disulfiram - like reaction with alcohol.
• Ampicillin: Also a penicillin - class antibiotic, it does not cause a disulfiram - like reaction when combined with alcohol.
• Cefotetan: Cephalosporins like cefotetan can have a disulfiram - like reaction with alcohol due to their chemical structure (they have a methyltetrazolethiol side chain similar to disulfiram - related compounds).
• Nitrofurantoin: This antibiotic does not typically cause a disulfiram - like reaction with alcohol.

Answer:

A. Metronidazole, D. Cefotetan