Question

multiple - choice question
which of the following statements best describes induced fit?
□ binding of substrate to the active site changes the shape of the active site of an enzyme.
□ binding of an activator molecule changes the shape of the active site of an enzyme.
□ substrate binds to an allosteric site rather than to the active site of an enzyme.
□ the conformation of the active site is determined by the tertiary or quaternary structure of the enzyme.
rewatch

Explanation:

Induced - fit model states that when the substrate binds to the active - site of an enzyme, the shape of the active - site changes to better accommodate the substrate. This is in contrast to the lock - and - key model. The binding of an activator molecule changing the active - site shape is related to allosteric regulation, not induced fit. Substrate binding to an allosteric site is incorrect as substrate binds to the active site in normal enzymatic reactions for induced fit. The determination of active - site conformation by tertiary/quaternary structure is a general fact about enzymes but not the definition of induced fit.

Answer:

Binding of substrate to the active site changes the shape of the active site of an enzyme.