Question

hormonal binding to receptors
what type of hormone can cross the plasma membrane to bind to a receptor in the cytosol or nucleus?
hydrophilic hormones
amine hormones
hydrophobic hormones
protein hormones

Explanation:

Hydrophobic hormones are lipid - soluble. The plasma membrane is made of a lipid bilayer. According to the principle of "like dissolves like", lipid - soluble (hydrophobic) hormones can easily cross the non - polar lipid bilayer of the plasma membrane. Once inside the cell, they can bind to receptors in the cytosol or nucleus. Hydrophilic hormones are water - soluble and cannot cross the lipid bilayer easily; they usually bind to cell - surface receptors. Amine hormones can be either hydrophilic or hydrophobic (e.g., epinephrine is hydrophilic, while thyroid hormones are hydrophobic, but the general class of amine hormones is not uniformly able to cross the membrane to bind to cytosolic/nuclear receptors). Protein hormones are large and hydrophilic, so they also bind to cell - surface receptors.

Answer:

Hydrophobic hormones