QUESTION IMAGE
Question
- the following reaction in gluconeogenesis circumvents the reaction catalyzed by pyruvate kinase in glycolysis.
pyruvate carboxylation
oxaloacetate transport into the cytosol
pyruvate decarboxylation
glucose - 6 - phosphate dephosphorylation
Brief Explanations
In gluconeogenesis, pyruvate carboxylation circumvents the pyruvate - kinase - catalyzed step in glycolysis. Pyruvate is carboxylated to oxaloacetate by pyruvate carboxylase, which is a key step to bypass the irreversible pyruvate kinase step in glycolysis.
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Pyruvate Carboxylation