Question

drag each tile to the correct box.
a woman was chopping vegetables when she accidentally cut her finger. a few days later, she observed a brownish layer on the wound on her finger. explain how the wound healed itself over time.
blood vessels dilate.
fibroblasts make collagen.
there is an aggregation of platelets.
neutrophils consume the bacteria.
the wound closes.
macrophages remove damaged tissue.

Explanation:

Step1: Recall wound healing stages

Wound healing has phases: hemostasis, inflammation, proliferation, maturation. First, blood vessels dilate (inflammation start, increase blood flow). Then platelets aggregate (hemostasis, form clot). Next, neutrophils consume bacteria (fight infection). Macrophages remove damaged tissue (cleanup). Fibroblasts make collagen (proliferation, tissue repair). Finally, wound closes (maturation, tissue remodels).

Step2: Order the events

1. Blood vessels dilate (inflammation initiation, increased blood to wound).
2. There is an aggregation of platelets (hemostasis, form platelet plug to stop bleeding).
3. Neutrophils consume the bacteria (inflammatory phase, fight infection).
4. Macrophages remove damaged tissue (inflammatory phase, clean debris).
5. Fibroblasts make collagen (proliferative phase, build new tissue).
6. The wound closes (maturational phase, tissue remodels and wound closes).

Answer:

1. Blood vessels dilate
2. There is an aggregation of platelets
3. Neutrophils consume the bacteria
4. Macrophages remove damaged tissue
5. Fibroblasts make collagen
6. The wound closes