Question

abnormal chromosomes are frequently found in cancerous malignant tumors. errors such as translocations may place a gene in close proximity to different control regions of the dna, which can make cells cancerous. which of the following might then occur to make the cancer worse?
○ a decrease in mitotic frequency
○ death of the cancer cells in the tumor
○ expression of inappropriate gene products
○ an increase in nondisjunction

Explanation:

When a gene is in close proximity to different control regions due to chromosomal abnormalities like translocations, it can lead to inappropriate gene expression. This is because the new control regions may regulate the gene in a way that is not normal for its function. For example, a tumor - suppressor gene might be placed near a highly active promoter (a control region) which could lead to its under - expression (if the promoter is not suitable for its normal regulation) or an oncogene might be over - expressed if placed near a strong promoter. An increase in nondisjunction is more related to errors in cell division (like in meiosis) rather than the effect of a gene's new location relative to control regions. A decrease in mitotic frequency would not make the cancer worse as cancer cells typically have a high mitotic rate. Death of cancer cells in the tumor would be a positive outcome (opposite of making cancer worse).

Answer:

expression of inappropriate gene products