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Question
which of the following types of diseases is associated with the philadelphia chromosome?
chronic myelogenous leukemia
down syndrome
klinefelter syndrome
heart disease
Chronic myelogenous leukemia (CML) is a type of blood - cancer. It is associated with the Philadelphia chromosome, which is an abnormal chromosome. The Philadelphia chromosome is formed by a reciprocal translocation between chromosome 9 and 22. This translocation leads to the formation of the BCR - ABL fusion gene, which is responsible for the development of CML.
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chronic myelogenous leukemia