Question

which of the following are examples of autosomal nondisjunction? select all that apply.
a) klinefelter syndrome
b) edwards syndrome
c) down syndrome
d) turners syndrome
e) patau syndrome

Explanation:

• Klinefelter syndrome (A): Caused by an extra X chromosome (\(XXY\)), related to sex - chromosome nondisjunction, not autosomal.
• Edwards syndrome (B): Caused by trisomy of chromosome 18 (autosome), due to autosomal nondisjunction.
• Down syndrome (C): Usually caused by trisomy of chromosome 21 (autosome), due to autosomal nondisjunction.
• Turner's syndrome (D): Caused by monosomy of the X chromosome (\(XO\)), related to sex - chromosome nondisjunction, not autosomal.
• Patau syndrome (E): Caused by trisomy of chromosome 13 (autosome), due to autosomal nondisjunction.

Answer:

B. Edwards syndrome, C. Down syndrome, E. Patau syndrome