Question

6 the pedigree shows the inheritance of a genetic condition in a family over two generations. which set of numbered individuals has the greatest chance of producing a child that is affected by this genetic condition? a 3 b 4 c 1 d 2

Explanation:

Step1: Analyze each pair

• Pair 1: One is carrier (female), one is normal (male). The probability of having an affected child is relatively low.
• Pair 2: Both are carriers. Using Punnett - square analysis (assuming the gene is \(A\) (normal) and \(a\) (mutant), \(Aa\times Aa\)), the probability of having an affected child (\(aa\)) is \(\frac{1}{4}\).
• Pair 3: One is affected (male), one is normal (female). If the trait is recessive, the probability of having an affected child depends on the female's genotype. If the female is homozygous normal (\(AA\)), the probability of having an affected child is \(0\).
• Pair 4: One is normal (male), one is carrier (female). The probability of having an affected child is relatively low.

Answer:

D. 2