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Question
on examination a female patient is found to have a tumor of the ovary. following removal of the tumor it is found to be an adenocarcinoma the cells of which have a \signet ring\ type of appearance. where did this tumor most likely originate? germ cells of the ovary hepatocytes mucosa of the cecum mucosa of the stomach
Signet ring cell adenocarcinoma is most characteristic of gastric (stomach) origin. Ovarian tumors with signet ring cells are often metastatic from the stomach (Krukenberg tumor). Germ cell tumors of the ovary don't have signet ring cells. Hepatocytes (liver) don't give rise to signet ring adenocarcinoma. Cecum mucosa (colon) adenocarcinoma has different features, not signet ring typical of stomach.
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D. Mucosa of the stomach