Question

chapter 26 apply what you learned question 5
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a tumor in a male patient is preventing the anterior pituitary from secreting lh. what effect will this have on his sperm production?

○ he will show a decrease in gnrh due to negative feedback and an increase in sperm production.

○ he will have a decreased amount of testosterone and in turn a decrease in sperm production.

○ he will have an increase in the production of androgen - binding protein and an increase in sperm production.

○ a decrease in lh will increase his levels of testosterone and increase sperm production.

Explanation:

To solve this, we analyze the role of LH (Luteinizing Hormone) in male reproductive physiology:

1. LH acts on Leydig cells in the testes to stimulate testosterone production.
2. Testosterone is essential for spermatogenesis (sperm production). If LH secretion is blocked by a tumor, Leydig cells will produce less testosterone.
3. Less testosterone will lead to a decrease in sperm production because testosterone is a key hormone for the process of making sperm.

Now let's analyze each option:

• Option 1: Negative feedback would actually increase GnRH (Gonadotropin - Releasing Hormone) if LH is low (since LH normally provides negative feedback on GnRH). Also, sperm production would decrease, not increase. So this is incorrect.
• Option 2: As explained, less LH means less testosterone from Leydig cells, and less testosterone leads to decreased sperm production. This matches our analysis.
• Option 3: Androgen - binding protein production is related to FSH (Follicle - Stimulating Hormone), not LH. Also, sperm production would decrease, not increase. So this is incorrect.
• Option 4: A decrease in LH leads to a decrease in testosterone, not an increase, and thus a decrease in sperm production. So this is incorrect.

Answer:

B. He will have a decreased amount of testosterone and in turn a decrease in sperm production.