Question

what type of chromosome mutation involves a fragment from one chromosome breaking off and attaching to another chromosome?
duplication
translocation
inversion
deletion
8
multiple choice 10 points
what is nondisjunction?
a change in protein structure
a type of gene mutation
a failure of chromosomes to separate properly
a type of mutation during dna replication
9
multiple choice 10 points
what is sickle cell anemia caused by?
a nutritional deficiency
a mutation in the hemoglobin gene
a bacterial infection
a viral infection
10
multiple choice 10 points
what happens if a person inherits one mutated gene for sickle cell anemia?
they will definitely get the disease
they will develop malaria
they will show severe symptoms
they will be a carrier but not show symptoms

Explanation:

• Question 8: Nondisjunction is defined as the failure of chromosomes to separate properly during cell division (such as meiosis). A change in protein structure is more related to issues like mis - folding (not directly nondisjunction). Gene mutation refers to changes in the DNA sequence of a gene, and mutation during DNA replication is a different type of genetic alteration.
• Question 9: Sickle cell anemia is a genetic disorder. It is caused by a mutation in the hemoglobin gene. Nutritional deficiency can cause other types of anemias (like iron - deficiency anemia), bacterial or viral infections are not the cause of sickle cell anemia.
• Question 10: Sickle cell anemia is an autosomal recessive disorder. If a person inherits one mutated gene (heterozygous state), they are a carrier. Carriers usually do not show the severe symptoms of the disease (which occur in the homozygous recessive state). They will not definitely get the disease (unless they inherit two mutated genes), and there is no direct link between inheriting one sickle cell gene and developing malaria.

Answer:

• Question 8: A failure of chromosomes to separate properly
• Question 9: A mutation in the hemoglobin gene
• Question 10: They will be a carrier but not show symptoms