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Question
what makes this individuals karyotype not normal? an extra sex chromosome a missing sex chromosome a missing autosome an extra autosome
A karyotype is a visual representation of an individual's chromosomes. In a normal human karyotype, there are 22 pairs of autosomes (non - sex chromosomes) and 1 pair of sex chromosomes (XX in females, XY in males). If there is a missing autosome, it disrupts the normal chromosome count and genetic balance. Missing an autosome is a more severe chromosomal abnormality compared to some sex - chromosome related issues (like having an extra sex chromosome in some cases may have less severe impacts in terms of basic survival and development in some syndromes). Autosomes carry a vast amount of genetic information crucial for various biological processes, and the loss of an entire autosome (monosomy for an autosome) is highly likely to cause significant developmental problems and is not a normal karyotype situation.
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A missing autosome