Question

as shown in figure 9.10 in the textbook, citrate is the initial carboxylic acid in the citric acid pathway and oxaloacetate is the final carboxylic acid. to determine whether the citric acid pathway was cyclic, hans krebs treated cells with radioactive oxaloacetate. what would have been the result of krebss experiment if the pathway were linear instead of circular? answer radioactive oxaloacetate + acetyl coa would produce radioactive glucose. radioactive oxaloacetate + acetyl coa would produce no radioactive citric acid cycle intermediates. radioactive oxaloacetate + acetyl coa would produce radioactive citric acid. radioactive oxaloacetate would produce radioactive acetyl coa. i dont know yet submit

Explanation:

If the citric acid pathway were linear, the radioactive oxaloacetate would only react once. In a linear pathway, there is no recycling. Oxaloacetate combines with acetyl - CoA to form citrate in the citric acid cycle. If it were linear, the reaction would stop after the first step of forming citrate (as there is no cycle to regenerate intermediates for further reactions). So, radioactive oxaloacetate + acetyl CoA would produce radioactive citric acid and then the pathway would stop (no further intermediates would be radioactive as there is no cycling to pass on the radioactivity further in the "linear" non - cycling process).

Answer:

Radioactive oxaloacetate + acetyl CoA would produce radioactive citric acid.