Question

as shown in figure 9.10 in the textbook, citrate is the initial carboxylic acid in the citric acid pathway and oxaloacetate is the final carboxylic acid. to determine whether the citric acid pathway was cyclic, hans krebs treated cells with radioactive oxaloacetate. what would have been the result of krebss experiment if the pathway were linear instead of circular? radioactive oxaloacetate + acetyl coa would produce radioactive citric acid. radioactive oxaloacetate would produce radioactive acetyl coa. radioactive oxaloacetate + acetyl coa would produce no radioactive citric acid cycle intermediates. radioactive oxaloacetate + acetyl coa would produce radioactive glucose. i dont know yet

Explanation:

In the citric acid cycle (Krebs cycle), oxaloacetate combines with acetyl - CoA to form citrate. If the pathway were linear, once oxaloacetate is used to form citrate (the first step in the cycle), there would be no recycling. So, radioactive oxaloacetate + acetyl CoA would produce no radioactive citric acid cycle intermediates as there is no circular flow to re - introduce the radioactive label into subsequent steps of what would be a linear pathway.

Answer:

Radioactive oxaloacetate + acetyl CoA would produce no radioactive citric acid cycle intermediates.