Question

question
diseases may arise when proteins fail to fold correctly in their last stages of processing and/or are directed towards the lysosome rather than towards the cell membrane. cystic fibrosis is an example of this type of disease. in cystic fibrosis, a functional ion channel is sent to the lysosome for destruction rather than being sent to the plasma membrane.
given this observation, the cellular component that is most likely the cause of the disease is the ______.
answer
○ golgi apparatus
○ lysosomes
○ ribosomes
○ peroxisomes
○ i dont know yet

Explanation:

To determine the cellular component causing the disease, we analyze each option:

• Golgi apparatus: It modifies, sorts, and packages proteins for transport (to membrane, lysosome, etc.). If it mis - sorts a functional ion channel to lysosome (instead of plasma membrane), it can cause diseases like cystic fibrosis.
• Lysosomes: Their role is to digest/break down substances. They don't sort proteins for transport to membrane, so not the cause here.
• Ribosomes: They synthesize proteins, not sort them for transport. So not responsible for mis - targeting.
• Peroxisomes: Involved in lipid metabolism and detoxification, not protein sorting for membrane/lysosome transport.

So the Golgi apparatus is the most likely cause as it's responsible for protein sorting and targeting.

Answer:

A. Golgi apparatus