Question

question 20 of 25
which mutation would likely have little to no effect on an individuals phenotype?
a. a frameshift mutation that caused a change near the active site of a protein
b. a substitution that replaced an amino acid with one that has similar properties
c. a deletion that caused misfolding of a protein
d. an insertion that produced a stop codon near the beginning of a gene

Explanation:

A substitution with similar - property amino acids may not disrupt protein function much. Frameshift (A) near active site, deletion (C) causing mis - folding, and insertion (D) with early stop codon are likely to have significant effects on phenotype. Similar - property amino acid substitution (B) is less likely to alter protein structure and function severely, thus having little to no effect on phenotype.

Answer:

B. A substitution that replaced an amino acid with one that has similar properties