Question

question 16 of 27
the table contains the dna sequence for a segment of the human insulin gene as well as the same dna sequence with a mutation.

original sequence	atg cgc ctc ctg ccc ctg ctg gcg
mutated sequence	atg cgc ctc cgc ccc tgc tgg cgc

which type of mutation occurred in the original sequence and generated the mutated sequence?
○ substitution
○ insertion
○ inversion
○ deletion

Explanation:

Compare the original and mutated DNA sequences. In the original sequence, we have "CTG" at certain positions. In the mutated sequence, these "CTG" are replaced with other base - pair combinations. For example, the fourth triplet: original is "CTG", mutated is "CGC" (a substitution of \(T\) with \(G\) in the second position of the triplet). Insertion would add new base - pairs, inversion would reverse a segment, and deletion would remove base - pairs. Since here base - pairs are replaced, it is a substitution mutation.

Answer:

A. substitution