Question

primary lateral sclerosis is a disease that affects the bodys ability to react to stimuli and causes a person to have difficulty moving the legs, body trunk, arms, hands, and face. which specialized cells are most affected by this disease? epithelial cells, hepatocytes neurons, epithelial cells muscle cells, neurons hepatocytes, muscle cells

Explanation:

1. Analyze the disease's effects: Primary lateral sclerosis affects the body's reaction to stimuli (involving neurons, which transmit signals) and movement (involving muscle cells, which contract for movement).
2. Evaluate each option:

• "epithelial cells, hepatocytes": Epithelial cells line surfaces, hepatocytes are liver cells—neither relate to stimuli reaction or movement. Eliminate.
• "neurons, epithelial cells": Epithelial cells are not involved in movement or stimulus response here. Eliminate.
• "muscle cells, neurons": Neurons handle stimulus response, muscle cells enable movement—matches the disease's effects.
• "hepatocytes, muscle cells": Hepatocytes are liver cells, irrelevant to stimulus reaction. Eliminate.

Answer:

muscle cells, neurons