Question

lipase is an enzyme that breaks down lipids in the digestive system of humans. it functions best at a ph range of 4.0 to 5.0. when a person takes an antacid tablet to relieve heartburn, the antacid increases the ph to around 7 in certain areas of the digestive system. which initial effect would most likely be caused by a change in ph?
1 more lipids would be digested.
2 fewer lipids would be digested.
3 the production of lipase molecules would increase.
4 the production of lipase molecules would decrease.

Explanation:

Enzymes like lipase have an optimal pH range for activity. Lipase functions best at pH 4.0 - 5.0. When antacid increases pH to around 7 (outside its optimal range), enzyme activity is affected. Enzyme activity is related to the rate of the reaction (lipid digestion here). A pH change away from the optimal range (increase from 4 - 5 to 7) will decrease enzyme activity. So, fewer lipids would be digested. The production of lipase molecules is regulated by genetic and cellular mechanisms and not directly by a one - time pH change in the digestive system.

Answer:

1. Fewer lipids would be digested.