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iso membranes are inside - out membrane vesicles used by researchers in membrane studies. as a molecule diffuses into the vesicle, it will encounter the layers of the membrane in the following order. head - tail - head - tail. head - head - tail - tail. head - tail - tail - head tail - head - head - tail tail - head - tail - head. submit previous answers request answer incorrect; try again; 5 attempts remaining
In a normal cell membrane, the phospholipid bilayer has hydrophilic heads facing outward and hydrophobic tails inward. In an inside - out vesicle (ISO membrane), the orientation is reversed. So, as a molecule diffuses into the vesicle, it first encounters the hydrophobic tail (from the outer leaflet of the original membrane, now inside the vesicle), then the hydrophilic head (from the inner leaflet of the original membrane, now on the inside of the vesicle), then another hydrophilic head (from the other side of the bilayer in the vesicle) and finally the hydrophobic tail.
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C. head - tail - tail - head