Question

an increase in unconjugated bilirubin is often found in each of the following conditions, except:
hemolytic anemia associated with excess hemolysis
gilbert disease
posthepatic biliary obstruction
jaundice during the neonatal period
hepatitis a

Explanation:

To solve this, we analyze each option:

• Hemolytic anemia (excess hemolysis) increases unconjugated bilirubin (UB) as more RBCs break down.
• Gilbert disease is a congenital disorder with impaired UB conjugation, raising UB.
• Posthepatic biliary obstruction (e.g., gallstones, tumors) causes conjugated bilirubin (CB) buildup (obstruction of bile flow), not UB.
• Neonatal jaundice often involves UB due to immature liver conjugation.
• Hepatitis A (viral hepatitis) can cause hepatocellular injury, sometimes with UB elevation (if liver’s conjugation is impaired).

Posthepatic obstruction primarily affects CB, while others relate to UB elevation.

Answer:

posthepatic biliary obstruction