Question

fill in the blank question
most endocrine systems are regulated through feedback, in which the secretion of the hormone counteracts the original change
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Explanation:

Negative feedback is a common regulatory mechanism in endocrine systems. In negative feedback, when a change (such as a change in hormone - related parameter like blood glucose level for insulin - glucagon system) occurs, the secretion of hormones acts to counteract that change. For example, if blood glucose rises, insulin is secreted to lower it. This is in contrast to positive feedback (which amplifies a change, like in the process of childbirth with oxytocin), and most endocrine systems use negative feedback for stable regulation.

Answer:

negative