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three factors that should be considered before beginning antimicrobial therapy are: the nature of the
\bcausing the infection, its degree of
\bto various drugs, and the overall medical condition of the patient.
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The question is about antimicrobial therapy and factors to consider, which relates to Medicine and Health (a subfield of Natural Science). The first blank likely refers to "susceptibility" (the microbe's susceptibility to drugs) and the second blank is "microorganism" (the nature of the microorganism causing infection).
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First blank: susceptibility; Second blank: microorganism