Question

required information
complement factors c5b + c6 + c7 + c8 make up a membrane attack complex that results in
multiple choice
enhanced phagocytosis
opsonization
cytolysis
the release of granzymes
the release of interferons

Explanation:

The membrane attack complex (MAC) is formed by complement factors C5b, C6, C7, and C8. MAC inserts into the target cell membrane and creates pores. This leads to an influx of water and ions into the cell, causing it to swell and eventually lyse.

• Enhanced phagocytosis is related to opsonins (like C3b) coating pathogens to facilitate phagocyte recognition, not MAC.
• Opsonization is the process of making pathogens more readily phagocytosed (again, due to opsonins like C3b, not MAC).
• The release of granzymes is part of the cytotoxic T - cell or natural killer cell mechanism (perforin - granzyme pathway, different from complement MAC).
• The release of interferons is an antiviral mechanism (signaling neighboring cells to resist viral infection, not related to MAC - mediated lysis).

Answer:

C. cytolysis