Question

multiple choice question
anemia may occur in the elderly due to gastric atrophy, which decreases secretion of which of the following?

intrinsic factor

kallikrein

factor x

erythropoietin

Explanation:

Gastric atrophy in the elderly can lead to decreased secretion of intrinsic factor. Intrinsic factor is necessary for the absorption of vitamin B12, and a deficiency of vitamin B12 can cause pernicious anemia. Kallikrein is related to the kinin - kininogen system, Factor X is involved in the coagulation cascade, and erythropoietin is mainly produced by the kidneys to stimulate red blood cell production. So the correct option is the one related to intrinsic factor.

Answer:

A. Intrinsic factor