Question

a 2 - year - old patient presents with hepatomegaly, splenomegaly, and enlarged lymph nodes. test results show positive for the philadelphia chromosome. what is your working diagnosis?
a) acute lymphocytic leukemia
b) acute lymphoblastic leukemia
c) hodgkin disease
d) non - hodgkin lymphoma

Explanation:

Acute lymphoblastic leukemia (ALL) is a type of cancer of the blood and bone marrow. It is the most common type of cancer in children. One of the key features in some cases of ALL is the presence of the Philadelphia chromosome. Hepatomegaly (enlarged liver), splenomegaly (enlarged spleen), and enlarged lymph nodes are also common manifestations in ALL. Acute lymphocytic leukemia is an older term and not the preferred nomenclature. Hodgkin disease and non - Hodgkin lymphoma are types of lymphoma (cancer of the lymphatic system) and do not typically have the Philadelphia chromosome as a key diagnostic feature in the context of a 2 - year - old with these symptoms.

Answer:

B. Acute lymphoblastic leukemia