Question

which type of graft rejection is caused by lymphocytes in grafted tissues causing systemic effects as they travel throughout the recipients body?
multiple choice

○ host versus graft rejection

○ graft versus host disease

○ xenograft rejection

Explanation:

To solve this, we analyze each option:

• Host versus graft rejection: Here, the host's immune system (not graft lymphocytes) attacks the graft. So this is incorrect.
• Graft versus host disease (GVHD): In GVHD, lymphocytes from the graft (donor) recognize the recipient's (host) tissues as foreign and attack, causing systemic effects as they travel. This matches the description.
• Xenograft rejection: This is rejection of tissue from a different species, and the mechanism here is about graft lymphocytes attacking the host, not xenograft-specific. So this is incorrect.

Answer:

B. Graft versus host disease