Question

which otc pain reliever can cause liver toxicity if taken in excess? *
ibuprofen
b. naproxen
c. aspirin
d. acetaminophen
pseudoephedrine is kept behind the counter because: *
it causes extreme drowsiness
it interacts with all otc drugs
it can be used to make illegal drugs
it is unsafe for adults

Explanation:

• For the first question: Acetaminophen (paracetamol) is metabolized in the liver. In excess, it can deplete glutathione, leading to the formation of a toxic metabolite (NAPQI) that causes liver damage. Ibuprofen and naproxen (NSAIDs) mainly have risks like gastrointestinal bleeding and kidney issues in excess. Aspirin in excess can cause salicylate toxicity (e.g., tinnitus, metabolic acidosis).
• For the second question: Pseudoephedrine is a precursor in the illegal synthesis of methamphetamine. It does not cause extreme drowsiness (it is a stimulant - like), it does not interact with all OTC drugs, and it is generally considered safe for adults when used as directed.

Answer:

• First question: D. Acetaminophen
• Second question: It can be used to make illegal drugs