Question

which is most likely a result of hypersecretion of growth hormone?
multiple choice
acromegaly
dwarfism
decreased plasma concentration of igf-i
decreased secretion of somatostatin
increased secretion of growth hormone-releasing hormone (ghrh)

Explanation:

• Acromegaly: Hypersecretion of growth hormone in adults leads to acromegaly. Bones (especially in hands, feet, face) and soft tissues grow abnormally.
• Dwarfism: Caused by hyposecretion (not hypersecretion) of growth hormone in childhood.
• Decreased plasma concentration of IGF - I: Growth hormone stimulates IGF - I production. Hypersecretion would increase (not decrease) IGF - I.
• Decreased secretion of somatostatin: Somatostatin inhibits growth hormone. Hypersecretion of growth hormone would likely be due to decreased inhibition (but this is a cause - not a result. The question asks for a result).
• Increased secretion of growth hormone - releasing hormone (GHRH): This is a cause (stimulates growth hormone release) - not a result of growth hormone hypersecretion.

Answer:

Acromegaly