Question

which of the following labs markers would be appropriate to evaluate if you suspected your patient had tissue damage?
a) esr
b) ast
c) crp
d) ldl
e) ldh

Explanation:

• AST (Aspartate Aminotransferase): Present in various tissues (like liver, heart, skeletal muscle). When tissue damage occurs (e.g., liver cell damage, heart muscle damage), AST leaks into the bloodstream, and its blood level can be measured.
• LDH (Lactate Dehydrogenase): Found in many tissues (such as heart, liver, skeletal muscle, red blood cells). Tissue damage leads to its release into the blood, and its concentration in blood can indicate tissue injury.
• ESR (Erythrocyte Sedimentation Rate): A non - specific marker of inflammation. While inflammation can be associated with tissue damage (as part of the body's response to injury), it is not as directly specific to tissue damage as AST or LDH in terms of being an enzyme released from damaged cells.
• CRP (C - reactive Protein): An acute - phase reactant, elevated in inflammation. It is more of a general marker of the inflammatory response rather than a direct indicator of tissue damage at the cellular level (like enzyme release).
• LDL (Low - Density Lipoprotein): Mainly related to lipid metabolism and a risk factor for cardiovascular diseases (atherosclerosis). It has no direct role in indicating tissue damage.

Answer:

B. AST, E. LDH