Question

which enzyme is responsible for gluing together the okasaki fragment on the lagging strand during dna replication?
ligase helicase dna polymerase amaylase

Explanation:

• Ligase: In DNA replication, DNA ligase catalyzes the formation of phosphodiester bonds between adjacent Okazaki fragments on the lagging strand, effectively "gluing" them together.
• Helicase: Unwinds the double - stranded DNA at the replication fork, but does not directly act on Okazaki fragments.
• DNA polymerase: Synthesizes new DNA strands (leading and lagging) by adding nucleotides, but its main role is not joining Okazaki fragments.
• Amylase: An enzyme involved in carbohydrate (starch) digestion in the digestive system, has no role in DNA replication.

Answer:

Ligase